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Nasal esketamine Spravato® is a nasal spray used for treatment-resistant depression.

Spravato® (Esketamine) Treatment in Cornelius and Mooresville, NC

A supervised, in-clinic option for adults with treatment-resistant depression

At Best Life Mental Health & Wellness, we provide REMS-certified Spravato® (esketamine) treatment for adults who have not experienced adequate improvement with traditional antidepressant medications.

Spravato is administered on-site in a controlled, medically supervised setting by trained clinicians in accordance with all REMS safety requirements.

Who Spravato May Be Appropriate For

Spravato may be considered for adults who:

Have tried two or more antidepressant medications without significant improvement
Experience persistent symptoms that interfere with daily functioning
Are working with a mental health provider and want to explore additional FDA-approved options

A full evaluation is required to determine whether Spravato is appropriate for each individual patient.

How Spravato Treatment Works

Spravato is a nasal spray administered in the clinic.
Your visit includes:

Pre-treatment assessment
On-site nasal administration
Monitoring for approximately two hours by a licensed provider
Safe discharge once clinical criteria are met

The treatment schedule typically includes twice-weekly visits initially, then gradual tapering based on clinical guidelines.

Safety Information & Monitoring

Because Spravato can cause temporary changes in blood pressure, alertness, and perception, it must be administered in a REMS-certified clinic with trained medical staff.

Commonly discussed considerations include: